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Jeff Ackerman Initiates Coverage On (NCEL) Starting This Morning
—Tuesday, November 4, 2025
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Freshly Listed On Nasdaq: (NCEL) Has Officially Begun Its Chapter As A Newly Listed Biotech Uniting Neuroscience And Regenerative Medicine.
Small Float: With Fewer Than 6M Shares Available, (NCEL)'s Small Float Could See The Potential For Big Moves If Demand Begins To Shift.
FDA Clearance: (NCEL) Has Received U.S. FDA Approval To Launch A Phase 2a Clinical Trial For AstroRx®, A Regenerative Therapy Targeting ALS.
Expanding Markets: (NCEL)'s Pipeline Targets Sectors Collectively Surpassing $300B In Projected Annual Potential Over The Coming Years.
Consider Starting Your Own Research On (NCEL)
Before The Bell Rings…
November 4, 2025
Minutes Away | See Why (Nasdaq: NCEL) Tops The Watchlist As The Bell Nears Dear Reader, We're just a few minutes away from the bell, have you started your own research on (NCEL) yet? Every so often, something rare happens in the biotech world—a quiet transformation that suddenly becomes impossible to ignore. Today, that moment belongs to NewCelX Ltd. (Nasdaq: NCEL)—a newly listed biotechnology company now stepping onto the global stage. After months of coordination, regulatory clearance, and shareholder approval, NewCelX has officially been listed on the Nasdaq Capital Market—marking the beginning of a company built to push the boundaries of neuroscience and regenerative medicine. The timing couldn't be more significant. The markets NewCelX Ltd. (Nasdaq: NCEL) is entering—neurodegenerative, metabolic, and central nervous system disorders—collectively represent well over $300B in combined annual potential over the next decade. Within that, the regenerative medicine field, valued at over $43B in 2025 and projected to surpass $212B by 2034, is driving a new era of medical innovation across the globe. 
That's where NewCelX Ltd. (Nasdaq: NCEL) is aiming to make its mark. But this isn't just a new name. It's the start of a new era for a biotech that now stands at the intersection of cell therapy, neuroscience, and global science leadership—linking Swiss precision, Israeli innovation, and U.S. visibility under one roof. And with that, NewCelX Ltd. (Nasdaq: NCEL) is topping our watchlist this morning—Tuesday, November 4, 2025—as the story of this newly listed biotech begins to unfold in real time. But keep in mind, (NCEL) has less than 6M shares listed in its public float. When floats are this small, there's the potential for big moves if demand begins to shift. A Quiet Transformation, Now Complete
Behind (NCEL) lies a story of reinvention that has spanned continents. What began as a focused Swiss biotech pursuing therapies for central nervous system disorders has now evolved—through a strategic merger—with one of Israel's leading cell-therapy innovators. The result: (NCEL), a next-generation biotechnology company developing both small-molecule and cell-based therapies that could reshape the treatment landscape for ALS, Type 1 diabetes, and CNS disorders. This merger fused complementary strengths—combining NLS Pharmaceutics' pharmacological expertise with Kadimastem's pioneering cell-therapy platform—to create a scientifically diverse, globally integrated biotechnology company. And now, with its Nasdaq listing complete, the world is seeing that transformation come to life. The Platform Powering (NCEL)'s Vision
What truly sets NewCelX apart is not just its global footprint or its leadership team—
it's the science at its core.
At the heart of the company lies a regenerative medicine platform built to produce "off-the-shelf" cell therapies capable of replacing, restoring, or repairing malfunctioning cells. These therapies are not theoretical—they are living, functional products developed from pluripotent stem cells and engineered to act like the body's own functional system. (NCEL)'s proprietary differentiation technology enables the generation of specialized, fully functional human cells, including astrocytes that protect neurons and insulin-secreting islet cells that naturally regulate blood sugar. Together, these form the foundation for three core programs—AstroRx®, IsletRx and DOXA—each targeting a different facet of neurodegenerative and metabolic disease. 
AstroRx®: A Regenerative Leap in ALS
Few diseases progress as rapidly or destructively as ALS. AstroRx® introduces a regenerative approach that targets the disease at its cellular root by transplanting lab-grown healthy and functional astrocytes directly into spinal fluid to protect and nourish neurons. After a successful Phase 1/2a study in Israel showing safety and efficacy by slowing disease progression, the FDA cleared a U.S. Phase 2a trial—positioning (NCEL) among the few advancing a stem-cell-based neurotherapy into clinical development. IsletRx: A Curative Approach for Diabetes
IsletRx uses lab-grown human islet-like cells that naturally sense blood sugar and release insulin—restoring the body's balance without lifelong immunosuppression. Preclinical data show sustained glucose control, and through a partnership with iTolerance Inc., (NCEL) is advancing iTOL-102,, which combines IsletRxcells with iTOL-100 microgel technology to enhance immune protection and long-term function. DOXA: A Multi-Target Innovation for the Brain and Beyond
The DOXA platform is designed to rebalance the brain's chemistry and repair disrupted pathways tied to sleep, inflammation, and metabolism. Its dual-action compounds activate orexin receptors and inhibit cathepsins, addressing both neuro and metabolic dysfunction. Early data indicate improved energy balance, reduced inflammation, and stronger β-cell stability—making DOXA™ a key complement to (NCEL)'s regenerative therapies. A Pipeline With Purpose
Each of (NCEL)'s core platforms—AstroRx®, IsletRx, and DOXA—represents a breakthrough in its own category. Together, they form a unified therapeutic ecosystem capable of tackling disease from multiple biological angles. This is not incremental innovation. It's a blueprint for the next generation of regenerative and precision medicine—where the boundaries between neurology, metabolism, and cell biology converge into one platform. Leadership with Proven Legacy
A science-first company needs proven leadership, and (NCEL)'s team brings decades of experience in bringing advanced therapies to market. Ronen Twito, Executive Chairman and Chief Executive Officer, leads the company through its next stage of growth, combining strategic execution with deep understanding of clinical development. Prof. Michel Revel, Chief Scientific Officer and Director, is globally recognized for his pioneering work in biotechnology. His discovery of Rebif®, a breakthrough therapy for multiple sclerosis, achieved over $2.4B in peak annual sales and has treated more than 1.5M patients worldwide. Supporting them are Alexander Zwyer (Director), Dr. Eric Konofal (Head of the DOXA Program), Prof. Ariel Revel, MD (Medical Director), and Dr. Kfir Molakandov (VP of R&D)—a team uniting clinical rigor, scientific excellence, and operational precision. A Global Foundation Built for Scale
(NCEL) operates across three continents—headquartered in Zurich, Switzerland, with R&D in Ness Ziona, Israel, and direct access to U.S. markets through its Nasdaq listing. This structure isn't just geographical—it's strategic. It allows (NCEL) to coordinate discovery, manufacturing, and commercialization efficiently across major biotech hubs, reinforcing its capacity to execute at scale. Why This Listing Matters Now The debut of (NCEL) comes at a pivotal moment in biotechnology. The convergence of neuroscience and regenerative medicine is driving renewed interest across the sector—where clinical-stage innovation is increasingly seen as the next frontier of therapeutic science. (NCEL)'s diversified portfolio, proven leadership, and recently cleared FDA pathway for AstroRx® position it as one of the few emerging biotechs bridging these worlds. From ALS to diabetes, from neuroprotection to regeneration, the company's mission is clear: To rebuild what disease destroys—cell by cell, pathway by pathway. A Multi-Sector Growth Story
The markets surrounding (NCEL) are massive—and expanding fast. The neurodegenerative disease market, spanning ALS, Alzheimer's, and Parkinson's, is projected to grow from $57B in 2025 to more than $81B by 2029, reflecting rising demand for next-generation therapies. Through AstroRx®, (NCEL) is advancing regenerative treatments that target these diseases at the cellular level. The metabolic disorder therapeutics market, including Type 1 and insulin-dependent diabetes, is estimated at $83B in 2025 and expected to exceed $120B by 2030. That's where IsletRx fits in—designed to restore natural insulin function and long-term glucose stability. The CNS therapeutics market—already among the largest in healthcare—is valued at roughly $127B in 2025, forecast to surpass $267B by 2034. With its DOXA platform targeting orexin signaling, inflammation, and metabolism, (NCEL) is positioned to advance innovation within this high-impact field. And anchoring it all, the regenerative medicine market—valued at over $43B in 2025 and projected to pass $212B by 2034—forms the foundation of NewCelX's vision. Together, these accelerating markets highlight why (NCEL)'s Nasdaq debut comes at the perfect moment—just as regenerative medicine and neuroscience converge to redefine modern biotechnology. 7 Reasons Why (NCEL) Is Topping Our Watchlist This Morning
—Tuesday, November 4, 2025
1. Freshly Listed On The Nasdaq: The newly listed (NCEL) has just begun trading under its new name, marking a pivotal moment for a biotech uniting neuroscience and regenerative medicine. 2. Small Float: With fewer than 6M shares in its public float, (NCEL) could see sharp movement if attention begins to shift its way. 3. FDA Clearance: (NCEL) has received U.S. FDA approval to begin a Phase 2a clinical trial for AstroRx®, its regenerative therapy designed to slow ALS progression. 4. Dual Strength: The formation of (NCEL) combined NLS Pharmaceutics' pharmacological background with Kadimastem's advanced cell-therapy expertise—creating a globally integrated biotech platform. 5. Global Footprint: With headquarters in Switzerland, R&D in Israel, and a U.S. market presence through Nasdaq, (NCEL) operates at the crossroads of three major biotech regions. 6. Expanding Markets: (NCEL)'s programs align with industries collectively exceeding $300B in projected annual potential, from neurodegenerative and metabolic diseases to regenerative medicine. 7. Proven Leadership: The company's Chief Scientific Officer, Prof. Michel Revel—creator of the multiple-sclerosis therapy Rebif®—brings a legacy of scientific success to (NCEL)'s next stage of growth.
Consider Starting Your Own Research On (NCEL)
Before The Bell Rings…
With its Nasdaq listing now complete, (NCEL) enters the spotlight as a biotech built for scale, science, and global reach. Its multi-platform foundation—spanning AstroRx®, IsletRx, and DOXA—positions it at the forefront of next-generation therapeutics for neurodegenerative and metabolic disease. We have all eyes on NewCelX (Nasdaq: NCEL) this morning—Tuesday, November 4, 2025.
Take a closer look before the bell rings. There's less than 10 minutes to go. Also, keep a lookout for my next update, it could be out to you any moment. Sincerely,
Jeff Ackerman
Managing Editor Stock News Trends
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